The Falcons (12-4-1) won their first region title in 10 years last week and carry a seven game winning streak into tonight's game.
Marshall County (16-4-1) beat Murray 3-0 to win the First Region title. The two teams were scheduled to play Sept. 22 but rain washed out the game.
The winner of tonight's game will host either Greenwood or Henderson County Wednesday night in the quarterfinals.
Because soccer isn't broken down into classes in Kentucky, Fort Campbell is the second smallest school competing in the state tournament, ahead of only Danville.